[Iatrogenic influence of testosterone therapy among persons with Klinefelter Syndrome].
نویسندگان
چکیده
The purpose of this work is a presentation of cases of persons with Klinefelter Syndrome where, most probably--as a result of testosterone supplementation therapy, some aggressive behaviours occurred requiring implementation of pharmacotherapy and psychiatric hospitalisation. The authors contemplate adequacy of standard hormone treatment where the main purpose is to improve the quality of life of the karyotype 47, XXY patients described. The article has been enhanced by a theoretical introduction into the basic subject which is the Klinefelter Syndrome.
منابع مشابه
Cse 27. Klinefelter Syndrome
Key Points Genetics ● Klinefelter syndrome should be considered as a possible diagnosis among adult men with hypogonadism, infertility, and/or low libido. ● Testosterone replacement therapy can improve the health of men with Klinefelter syndrome. Ethics ● Almost all men with Klinefelter syndrome are infertile, which may raise questions of paternity if an affected male has a child. ● The implica...
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Hypogonadism is reported to be an independent risk factor for the development of central obesity in men, and epidemiologic studies indicate an inverse relation between serum testosterone and obesity [1]. In patients with prostate cancer, androgen deprivation therapies increased body fat mass [2], whereas it is known that androgen can prevent the differentiation of pluripotent cells into an adip...
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PURPOSE Klinefelter syndrome (KS) is related to testicular insufficiency, which causes low testosterone levels in serum. Generally, sex hormone levels and bone mineral density (BMD) are lower in patients with KS than normal. We investigated the effects of testosterone replacement on serum testosterone levels and BMD in KS patients. MATERIALS AND METHODS From December 2005 to March 2008, 18 KS...
متن کاملRecommendations on the diagnosis, treatment and monitoring of hypogonadism in men
Hypogonadism or Testosterone Deficiency (TD) in adult men as defined by low levels of serum testosterone accompanied by characteristic symptoms and/or signs as detailed further on can be found in long-recognized clinical entities such as Klinefelter syndrome, Kallmann syndrome, pituitary or testicular disorders, as well as in men with idiopathic, metabolic or iatrogenic conditions that result i...
متن کاملNeuroendocrinology Letters Vol. 25 No.6, December 2004
AIM OF THE STUDY: The investigation of the influence of anti-opioid drug on hypophyseal and gonadal hormones secretion in case of Klinefelter syndrome. MATERIAL AND METHODS: The naloxone test (0,4 mg iv) was performed in 14 patients with Klinefelter syndrome aged from 19 to 32 and in 12 age matched control subjects with azoospermia and normal spermatogenesis in testicular histology. The plasma ...
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عنوان ژورنال:
- Psychiatria polska
دوره 45 1 شماره
صفحات -
تاریخ انتشار 2011